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ASCP Exam Tip: Resolving ABO Discrepancies 🆎🅾️🩸 ABO discrepancies happen when your forward grouping and reverse grouping don’t agree. 🚨 Your cells say one thing, your plasma says another and now you have no choice but to figure out why before you can give the patient blood safely. The 4 major causes? 1️⃣ Technical errors 2️⃣ Weak or missing antibodies 3️⃣ Extra antibodies or rouleaux (cold agglutinins or other alloantibodies) 4️⃣ Subgroups of A or B (like A2 with anti-A1 or acquired B phenom
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