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0:13
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Knowledge Pill MD
The Clotting Mutation – Medical Must Knows Pathology #9
Explanation: 🩸 Factor V Leiden mutation is the most common inherited thrombophilia. It causes resistance of factor V to inactivation by activated Protein C (APC), leading to excessive clot formation and an increased risk of venous thromboembolism. Antithrombin deficiency (A): Rare; it leads to unregulated thrombin activity but is much less ...
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