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Learn what noncompetitive inhibition is. Explore how a noncompetitive inhibitor affects enzyme action, aided by enzyme inhibition graphs and examples.
31K viewsJun 4, 2016
Uncompetitive inhibition Mechanism
SOLVED: EverythingSome enzymes are inhibited by high concentrations of their own substrates by an uncompetitive inhibition type mechanism. Calculate the modified rate expression for an enzyme that exhibits autoinhibition. Use your equation to calculate an expression for the substrate concentration at which the maximum is obtained. Let's call this value Vmax observed. It is different from the usual parameter Vmax in the MM expression. Use a computer to create a plot of v vs [S] over a range of [S
SOLVED: EverythingSome enzymes are inhibited by high concentrations of their own substrates by an uncompetitive inhibition type mechanism. Calculate the modified rate expression for an enzyme that exhibits autoinhibition. Use your equation to calculate an expression for the substrate concentration at which the maximum is obtained. Let's call this value Vmax observed. It is different from the usual parameter Vmax in the MM expression. Use a computer to create a plot of v vs [S] over a range of [S
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