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Metformin Mechanism of Action & Side Effects (Pharmacology Animation)
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Metformin doesn’t work by forcing your pancreas to make more insulin like many people think. Its main job is actually in the liver—helping reduce excess glucose production, improving insulin sensitivity, and helping your body use sugar more efficiently. That’s why it remains one of the first-line treatments for type 2 diabetes. #Metformin #Diabetes #Type2Diabetes #Pharmacology #HealthcareEducation
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For over 60 years, we thought metformin worked mainly through the liver and gut. But new research suggests the brain may play a major role too. This study identified a specific brain pathway (Rap1 in the hypothalamus) that appears critical to metformin’s glucose-lowering effects, potentially reshaping how we understand one of the world’s most prescribed diabetes medications. Source: Sci. Adv. 2025;11:eadu3700
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Metformin is the most common diabetes medicine — but long-term use can secretly lower your Vitamin B12 levels! It interferes with calcium-dependent absorption in the intestine, leading to fatigue, numbness, and even nerve damage. Watch till the end to understand how this happens and why regular B12 check-ups matter. 👉 Follow Dr UUT lectures for more hidden drug facts and medical awareness. #Metformin #VitaminB12Deficiency #DiabetesAwareness #druutlectures #DrugFacts
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There is increasing evidence that metformin hinders vitamin B12 absorption. One of the leading theories is that metformin antagonizes the intrinsic factor-vitamin B12 complex. If you’re on metformin, you should do routine B12 monitoring with the rest of york blood work. #metformin #metformin #b12 #vitaminB12 #vitaminb12deficiency
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LONG TERM SIDE EFFECTD OF METFORMIN Long term problems with Metformin a medication used to control high blood sugar and treat type 2 diabetes. • Overview: Metformin is commonly used to control blood sugar levels in Type 2 diabetes. While generally safe, long-term use can lead to certain side effects. • Relevant Information: Common side effects of metformin include gastrointestinal issues such as nausea, vomiting, diarrhea, stomach ache, loss of appetite, and a metallic taste. A rare but serious
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