The proton gradients that power respiration are as universal as the genetic code itself, giving an insight into the origin of life and the singular origin of complexity. Why do virtually all cells ...
Each year, about 1,000 to 4,000 children in the United States are born with a mitochondrial disease. Many of these diseases are tied to a deficiency in ATP synthase thought to be triggered by ...
F-Type ATP synthase, a catalytic complex of proteins, synthesizes adenosine triphosphate (ATP), the energy currency of living cells. A lot of ambiguity exists over the rotational mechanism of this ...
Recently, a research team led by Professor Hongzhe SUN from the Department of Chemistry, Faculty of Science, The University of Hong Kong, has published a paper in Nature Communications. The ...
Mitochondrial dysfunction, including decreased mitochondrial respiration and increased mitochondrial stress, is associated with many major human diseases and casual to many pathological defects.
A recent study explains an essential component for proper mitochondrial function: The protein complexes MICOS and ATP synthase can communicate with each other. Researchers have uncovered an important ...
Novel compound attacks tuberculosis bacteria's ATP synthase, showing promise against drug resistance
Researchers at Martin Luther University Halle-Wittenberg (MLU) have developed a promising new substance for targeting bacteria that cause tuberculosis. The team have produced a compound that inhibits ...
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