Department of Biomedical Engineering, Pennsylvania State University, University Park, United States Department of Mathematics, Tulane University, New Orleans, United States Department of Chemistry, ...

Summary: Researchers have identified a previously unknown “hook-like” domain in the tail of the kinesin-2 motor protein that explains how these molecular machines select the right cargo inside cells.

Abstract: Mechanical stress on cells is transmitted through many biological processes, for example, cell shape control, tissue patterning, and axonal homeostasis. Microtubules, a cytoskeletal ...

Most of us will probably be able to recall at least vaguely that a molecule called ATP is essential for making our bodies move, but this molecule is only a small part of a much larger system. Although ...

IPS and VA displays are two of the most common and enduring LCD display types, with years of use in cutting-edge monitors and televisions, and they’re still competing with the likes of modern OLED ...

Introduction: The post-mitotic cardiomyocyte (CM) must maintain proteostasis while also preserving the ability to remodel, particularly during times of cardiac growth. How the CM couples transcription ...

Cytoskeletal motor proteins are essential molecular machines that hydrolyze ATP to generate force and motion along cytoskeletal filaments. Members of the dynein and kinesin superfamilies play critical ...

Regulation of organelle transport by molecular motors along the cytoskeletal microtubules is central to maintaining cellular functions. Here, we show that the ubiquitous tau-related ...