Shannon O'Brien, 28, was an apparent innocent victim, "simply doing her job when her life was tragically taken," police said.

Chuck Negron, one of the founding members of "One" and "Til the World Ends" rockers Three Dog Night, has died.

Get a quick digest of today's top local news stories from St. Louis Post-Dispatch. (7) updates to this series since 31 mins ago Donovan becomes the fourth All-Star traded this winter, and the return ...

The federal agency for protecting workers’ civil rights revealed Wednesday that it is investigating sportswear giant Nike for allegedly discriminating against white employees through its diversity ...

Aaliyah Moorehead, 31, of St. Louis, was held Thursday night in the St. Louis County Justice Center on charges of first-degree assault, endangering the welfare of a child and three ...

Hamilton served for 34 years as a Democratic member of the U.S. House, forging deep friendships across the aisle with Republicans.

Lab-grown diamonds may help reduce cost barriers and address ethical considerations that often give buyers pause.

NBC’s Today show co-anchor, Savannah Guthrie’s 84-year-old mother, Nancy Guthrie, is missing. Here is everything to know ...

Terrance Christopher Smith, 49, was being held Wednesday at the St. Louis County Justice Center on $100,000 cash bond.

St. Charles County has joined the Notary Fraud Alerty system, which allows registered notaries to get an alert whenever ...

William Stevenson, 77, was charged with murder in the death of his wife, who was found unresponsive in their home on Dec. 28, police say.

Newly released autopsy reports confirm Spencer and Monique Tepe’s official causes of deaths and reveal further details about ...