Bilirubin, the primary breakdown product of hemoproteins, particularly hemoglobin, plays a key role in the diagnosis, prognosis, and monitoring of liver diseases. In acute liver diseases, such as ...

One in eight newborn babies has a gene variant that almost completely protects against jaundice. The research provides the opportunity to develop a treatment that can prevent severe cases of jaundice.

"This enzyme converts bilirubin into a variant that is water-soluble, allowing the body to get rid of the bilirubin. We are surprised that we only see this effect in the intestines of the babies, but ...

Inherited hyperbilirubinemia, encompassing Gilbert syndrome, Crigler-Najjar syndrome, Dubin-Johnson syndrome, and Rotor syndrome, represents a spectrum of disorders rooted in genetic defects affecting ...