Alida Biosciences’ EpiPlex platform uses robust assay controls and specialized bioinformatics to detect RNA modification, genomic coordinates, and relative quantity.
In recent years, there has been a rapid increase in the discovery of bacterial immune systems: groups of genes that enable bacteria to protect themselves against viruses known as bacteriophages 1.
N4-Acetylation of cytidine (ac4C) is an mRNA modification that enhances cellular mRNA stability and translation. Most eukaryotic organisms catalyze ac4C using a homologue of human N-acetyltransferase ...
This technical note explores a novel poly(A) tail modification that enhances total protein expression and extends expression ...
By casting doubt about the promise of mRNA tech, RFK Jr. is slowing progress toward highly effective therapies that could ...
The US health secretary claimed mRNA vaccines are ineffective against respiratory diseases, while announcing he was cutting half a billion dollars in funding for mRNA vaccine development. But this ...
Recently, demands in RNA manufacturing for long-chain RNAs exceeding 100 nucleotides, such as single guide RNA (sgRNA) for genome editing, have been increasing. Generally, these types of RNA are ...
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