Microcrystal electron diffraction (MicroED) has advanced structural methods across a range of sample types, from small molecules to proteins. This cryogenic electron microscopy (cryo-EM) technique ...

A collection of protocols detailing sample preparation, experimental acquisition and data analyses approaches using electron microscopy and electron tomography based methods. This protocol describes ...

Microbiome research often involves complex workflows and laborious manual sample preparation protocols. Labs using manual pipetting approaches frequently suffer from limited throughput and high ...

Sample preparation is essential when employing chromatography for bioanalytical analysis as system performance will be negatively affected if it is not performed. Preparation methods include protein ...

Next-generation sequencing (NGS) is increasingly employed to dive deeper into complex biological mechanisms in a myriad of disciplines. But as with most methodologies, the quality of the input ...

The translation of biomarker discoveries into diagnostic applications relies on the robustness of clinical proteomics. Achieving high-throughput, reproducible results requires careful attention to ...

Sample preparation plays a crucial role in bioanalytical analysis involving chromatography. Insufficient sample preparation, such as skipping protein precipitation, phospholipid removal (PLR), ...