For decades, scientists have known that motor proteins like kinesin-2 ferry vital cargo along microtubule "highways" inside cells. But how these molecular vehicles identify and bind to the right cargo ...
The kinesin-2 motor protein uses a hook-like adaptor and cargo-binding (HAC) domain to recognize and transport cargo along microtubule highways, revealing a cellular logistics system critical for ...
The smallest proteins travel in our cells, completing deeply important tasks to keep our molecular mechanisms moving. They are responsible for transporting cargo, duplicating cells and more. Now, a ...
These include oxidative stress, neurodegeneration, protein aggregation, mitochondrial dysfunction, and microtubular transport impairments. In this article, microtubular transport in neurons will be ...