Recent work has shown us that G3BP nucleation of stress granules in the absence of virus infection activates PKR, resulting in phosphorylation of eIF2alpha and activation of NF-kB and JNK signal ...

Stress granules are droplet-like protein hubs that temporarily shield fragile RNA from cellular stresses such as toxins. VCP is a protein essential for breaking up stress granules and has been linked ...

Scientists from St. Jude Children's Research Hospital and Washington University in St. Louis report mechanistic insights into the role of biomolecular condensation in the development of ...

Stress granules are droplet-like protein hubs that temporarily shield fragile RNA from cellular stresses such as toxins. VCP is a protein essential for breaking up stress granules and has been linked ...

Cells inherit protection from one of the sun’s overlooked harms—UV-damaged RNA. Although the harms of UV-damaged RNA aren’t as well recognized as the harms of UV-damaged DNA, they shouldn’t be ...

Cells respond to cellular stress by forming stress granules, molecular condensates containing non-translating messenger ribonucleoproteins. Stress granules form during chemotherapy and promote cell ...

Scientists from St. Jude Children's Research Hospital and Washington University in St. Louis report mechanistic insights into the role of biomolecular condensation in the development of ...

(MEMPHIS, Tenn. – October 8, 2025) Stress granules are droplet-like protein hubs that temporarily shield fragile RNA from cellular stresses such as toxins. VCP is a protein essential for breaking up ...

A recent study has unveiled an exciting discovery about how our cells defend themselves during stressful situations. The research shows that a tiny modification in the genetic material, called ac4C, ...

(MEMPHIS, Tenn. and ST. LOUIS, MO.– May 28, 2025) Scientists from St. Jude Children’s Research Hospital and Washington University in St. Louis report mechanistic insights into the role of biomolecular ...