Choosing the proper sample size for an investigation is one of the crucial jobs required of a statistician. Regardless of whether the statistician is deciding the number of patients to select in a ...

Implementation of the Time-to-Event Continuous Reassessment Method Design in a Phase I Platform Trial Testing Novel Radiotherapy-Drug Combinations—CONCORDE BayeSize applies the concept of effect size ...

Case-control studies are among the most commonly used means of assessing association between exposure and outcome. Sample size determination and the optimal control-to-case ratio are vital to the ...

Sample size determination is an important component of study design and can frequently be addressed using the multinomial probability model. The sample size determination procedures of Tortora and ...

Yan Zhuang specializes in the areas of sequential analysis, sampling strategies, sample size determination, and statistical inference. She also enjoys working with people from other disciplines to ...

Reporting of sample size calculations was also lacking. Twelve RCTs specified QOL as a primary end point; however, only seven detailed the sample size calculation. There was no consistent basis for ...