RNA therapeutics open up new possibilities for the targeted and precise treatment of diseases. To ensure that RNA molecules ...
A new review in Molecular Cancer maps the bidirectional crosstalk between deubiquitinases and m6A RNA modification, revealing ...
To overcome these limitations, the research team developed a "targeted RNA acetylation system (dCas13-eNAT10)" by combining Cas13, gene scissors that precisely target desired RNA, with a hyperactive ...
Short-read RNA sequencing reporting the modifications that alter protein output is starting to make epitranscriptomics ...
A new review in Genes & Diseases highlights FTO, an enzyme involved in RNA modification, as a potentially important biomarker and therapeutic target across gastrointestinal cancers.
Newswise — Researchers from the Third Affiliated Hospital of Guangzhou Medical University, et al. have conducted a review entitled “Regulations of m⁶A and other RNA modifications and their roles in ...
A Northwestern Medicine study published in the Journal of Clinical Investigation has uncovered a connection between a well-known cancer-related protein and a major RNA modification process, which may ...
Cells contain a blueprint in the form of DNA that dictates what they can make. This blueprint is converted into a message (mRNA), which is then converted into a protein. Although DNA remains the same ...
Ovarian cancer remains the deadliest of the gynecologic malignancies, a distinction earned not because it is the most common ...
Scientists at the UCLA Health Jonsson Comprehensive Cancer Center and the University of Toronto have revealed how a tiny chemical modification in RNA, known as m 6 A, plays a critical role in the ...
A new tool called SigRM helps researchers study RNA modifications in individual cells, improving our understanding of how genes are regulated. Researchers have developed a new tool that will help ...
RNA plays critical roles in nearly all biological processes, but current methods for sequencing RNA are significantly limited. This is partially because RNA molecules are chemically modified within ...