The hypothalamus–pituitary–target gland axis has been recognized as a fundamental functional framework of the mammalian endocrine system. The anterior pituitary gland synthesizes and secretes multiple ...

Patients with primary and secondary empty sella show distinct clinical and endocrine trajectories over a median follow-up of ...

An unexpected observation has led researchers at the Weizmann Institute of Science to challenge a 200-year-old doctrine regarding the embryonic origins of the pituitary gland. Situated at the base of ...

Pituitary tumours are common and cause unrestrained hormone secretion or compression of intracranial structures. Treatment aims to suppress hormone hypersecretion, ablate tumours or prevent their ...

A team of researchers at the IRCM, supervised by Dr. Jacques Drouin, reprogrammed the identity of cells in the pituitary gland and identified critical mechanisms of epigenetic cell programming. This ...

Located at the base of the brain, nestled within the skull, lies a bean-shaped endocrine gland called the pituitary. It’s as small as a pea and just about as light – weighing only half a gram. But ...

Changes clinical practice: Adults who received cranial radiotherapy for nonpituitary tumors should have their hypothalamic-pituitary axis periodically evaluated. This is the first meta-analysis of ...

Learn how to manage persistent acromegaly symptoms after normal lab results, including monitoring, causes of lingering issues ...

For permission requests, please contact NEJM Reprints at [email protected] In spite of great progress in the knowledge of the chemistry and physiologic function of the pituitary hormones no truly ...

Background A 61-year-old lady was admitted to hospital with sepsis due to a urinary tract infection. Three days after admission, she suddenly started to have severe headache with visual disturbance ...

Known as the master gland, the pituitary gland is behind the bridge of the nose. Medically reviewed by Isabel Casimiro, MD, PhD The pituitary gland, known as the master gland, helps regulate most of ...