Cilia are multifunctional organelles that are constructed using intraflagellar transport (IFT) of cargo to and from their tip. It is widely held that the retrograde IFT motor, dynein-2, must be ...

Two-legged protein motors are currently marching around your cells delivering cargoes to precise locations, and with impeccable timing. These motors are transporting energy-producing mitochondria to ...

The smallest proteins travel in our cells, completing deeply important tasks to keep our molecular mechanisms moving. They are responsible for transporting cargo, duplicating cells and more. Now, a ...

Biophysicists and a plant biologists have discovered a novel motor protein that significantly expands current understanding of the evolution and design principle of motor proteins. A research team led ...

Intracellular transport is interspersed with frequent reversals in direction due to the presence of opposing kinesin and dynein motors on organelles that are carried as cargo. The cause and the ...

PHILADELPHIA – Researchers at the University of Pennsylvania School of Medicine discovered that proteins carrying chemical cargo in nerve cells react differently when exposed to the tau protein, which ...

This is a preview. Log in through your library . Abstract We report an ATPase activity, present in sea urchin egg cytosol, that is activated by microtubules. The activity sediments at 10 S in sucrose ...

These include oxidative stress, neurodegeneration, protein aggregation, mitochondrial dysfunction, and microtubular transport impairments. In this article, microtubular transport in neurons will be ...