Why does the COVID-19 virus make some people sicker than others? For years, scientists have looked to a critical piece of immune system machinery - known as the interferon pathway - for answers. There ...

The assay is fast and simple and has already shown clinical utility, although its interpretation may be limited by reference ...

Researchers from Oncovalent Therapeutics Inc. recently provided details on the discovery and preclinical evaluation of SB-4826, a first-in-class oral, covalent small-molecule inhibitor of the SUMO ...

The regulation of type I interferon (IFN-1) signaling is crucial for fine-tuning the innate immune response to combat pathogens, fight cancer and prevent autoimmune diseases. Disrupted IFN-1 signaling ...

Immunotherapy with immune checkpoint inhibitors is standard first-line treatment for advanced renal cell carcinoma (RCC), but ...

Please provide your email address to receive an email when new articles are posted on . Research will follow up on the recent discovery of interferon response gene signatures in patients with EoE.

To evaluate the safety of sequentially administered recombinant (r) human (h) interleukin-12 (IL-12) and interferon alfa-2b (IFN-α-2b) in patients with advanced cancer and to determine the effects of ...