In a study published in Cell, a research team led by ZHANG Yong'e and WANG Haoyi from the Institute of Zoology of the Chinese Academy of Sciences has characterized the diversity of DNA transposons and ...
Transposable elements (TEs) make up a large proportion of eukaryotic genomes. As their mobilization creates genetic variation that threatens genome integrity, TEs are epigenetically silenced through ...
Understanding transposons provides a new starting point to generate more powerful gene editing tools
CRISPR has ushered in the era of genomic medicine. A line of powerful tools has been developed from the popular CRISPR-Cas9 to cure genetic diseases. However, there is a last-mile problem – these ...
Stable, high-expressing cell lines are a critical component in commercial manufacturing of therapeutic proteins and vaccines. But the time and cost of developing these lines is exacerbated by the ...
Genetic engineering in non-human primates has been challenged by the limitations of virus-based gene delivery methods. Recently, researchers in Japan successfully used a nonviral system to introduce a ...
The first transposon that can determine survival in mammals has been identified, raising questions about evolution and fertility in the class. Transposons are DNA sequences initially incorporated into ...
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