Traditional bisulfite sequencing damages DNA, while enzyme-based alternatives are inconsistent. A novel methylation analysis method, called UMBS-seq, has been published in Nature Communications.

A new long-read DNA test improves rare disease diagnosis, replaces multiple existing tests, and could become the preferred ...

The epigenetic modification, DNA methylation, is characterized by 5-methylcytosine (5-mC) and found in specific genomic locations, most notably regulatory regions such as promoters and enhancers.

Cyprus has begun using an advanced DNA testing method to identify the remains of Greek Cypriot soldiers and civilians who went missing during the Turkish invasion of 1974 after conventional techniques ...

Definition: DNA amplification is the laboratory process of making many copies of a selected DNA sequence from a very small starting amount. It allows DNA that would otherwise be too scarce to detect ...

PCR genetic analysis has been in the spotlight since COVID-19, but light is now further facilitating PCR-free methods. Osaka Metropolitan University scientists have developed a light-induced DNA ...

Quantitative polymerase chain reaction (qPCR) is a molecular technique that has reshaped the landscape of biological research and medicine due to its high sensitivity and specificity. qPCR, also known ...