Objective: Dynamically regulated expression of the gap junction protein connexin (Cx)43 plays pivotal roles in wound healing. Cx43 is normally downregulated and Cx26 upregulated in keratinocytes at ...

Worldwide, an estimated 95 million people suffer from wounds that result in tissue loss. While acute wounds heal uneventfully, chronic wounds such as ulcers do not and often persist for months or ...

This news release is available in Japanese. The downregulation of spinal astrocyte connexin43 (Cx43) expression causes sustained neuropathic pain following peripheral nerve injury. The inflammatory ...

The astroglia (a class of neural cells) of patients with MS overproduce a channel protein known as connexin 43. This overproduction facilitates the release of pro-inflammatory chemicals that trigger a ...

The CX43 microscope enable users to remain comfortable during long periods of routine microscopy observations. The microscope frame conforms to the user’s hands and the location of the control knobs ...

Experiments with the protein Cx43 show that it could be a "druggable target" to prevent renal decline. A new study from the United Kingdom has shed light on an emerging area of research in chronic ...

TAT-Cx43 (266-283) shows potential for treating glioblastoma multiforme Dec. 5, 2024 ...