Pulmonary hypertension (PH) is a global health issue characterized by high mortality. The main targets for current therapies in PH focus on the prostacyclin, nitric oxide, and endothelin pathways.

Neurons with approximately billion units are found throughout the body. The nervous system is the dominant regulatory system in the human body. In terms of function and location, the nervous system is ...

FGF21 is primarily known as a metabolic hormone. A new study by researchers at Helmholtz Munich and Ludwig Maximilians ...

One finding of the study, now published in the Journal of Biological Chemistry, surprised the researchers: The mice were simultaneously protected against hypertension by activating a different ...

Autophagy is essentially the 'rubbish collection' of our cells. If there are problems in this process, which is so important for our health, diseases such as Parkinson's can result. In their latest ...

Sepsis is a complex clinical syndrome characterized by dysregulated immune responses, systemic inflammation, and multi-organ dysfunction. It involves intricate interactions among multiple signaling ...

Researchers at ETH Zurich have identified a compound that blocks the aggregation of GRK2, a kinase protein whose clumping ...

Microtubules, part of heart muscle cells' internal "skeleton," help determine how the heart changes shape under stress, and a ...

• BTK inhibitors work by targeting and blocking the BTK enzyme, which is crucial for the survival and growth of cancerous B-cells in mantle cell lymphoma (MCL). This cuts off the cancer cell’s support ...

Researchers enclosed the cells within tiny alginate hydrogel capsules and embedded them inside a flexible, biocompatible ...

A Yale-led study uncovered unexpected communication between retinal visual pathways that were thought to operate separately.