The enzyme RNA polymerase II transcribes genes into messenger RNA. This process is guided by modifications to the enzyme's ...

A new study reveals that specific chemical signals, generated within the energy-producing structures of the brain’s support ...

Replacing APOE4 with APOE2 in adult mice rapidly reshapes brain lipids and gene expression, even after development is ...

Blocking the action in cancer cells of a key protein reduced by up to 80% tumor growth in mice with a common type of lung cancer.

NYU Langone Health researchers found that a type of cell death caused by a buildup of highly reactive molecules suppresses ...

Direct contact with ESCC cells leads mesenchymal stem cells (MSCs) to become cancer-associated fibroblast (CAF)-like cells, which secrete periostin and activate the Akt and extracellular ...

Yale School of Medicine (YSM) researchers have made key breakthroughs in understanding how to treat fibrotic diseases such as ...

Researchers at Weill Cornell Medicine report that a rare gene mutation that delays Alzheimer’s disease does so by damping inflammatory signaling in brain-resident immune cells in a preclinical study.

Mitochondrial defects are associated with the development of diseases such as type 2 diabetes (T2D). Studies in mice and in human tissues, by researchers at the University of Michigan, have now found ...