Endothelial-to-Osteoblast Conversion (EC-to-OSB) regulates bone formation and homeostasis via the Kindlin-2/Piezo1/TGFβ/Runx2 axis. Reduced Kindlin-2 in endothelial ...
Scientists develop a new material that protects stem cells and helps repair facial bone damage by reducing harmful stress and inflammation in the body. (Nanowerk Spotlight) Maxillofacial bone defects ...
The field of bone and joint disease research has increasingly focused attention on the multifaceted roles of osteoclasts in both physiological and ...
A recent study identifies Neural EGFL-like 2 (NELL2), a secreted protein, as a key regulator of bone homeostasis, offering potential therapeutic applications for osteoporosis. NELL2 promotes ...
A newly discovered receptor switch that boosts bone growth could transform how we treat osteoporosis, by stimulating the body’s own bone-building machinery using a targeted drug and even mechanical ...
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Unfolded protein response pathway offers new targets to treat bone weakness in cancer patients
Before a chain of amino acids can become an active and useful protein, it must be processed and folded into the appropriate conformation. Much of this processing occurs in the endoplasmic reticulum ...
Studies by University of Birmingham researchers suggest that a naturally occurring peptide known as PEPITEM (Peptide Inhibitor of Trans-Endothelial Migration), could represent a promising potential ...
If you are one of the lucky few who doesn’t experience some degree of lactose intolerance, you’re in luck. According to a recent study, eating dairy can actually be pretty beneficial to our ...
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