These resorption and formation phases are linked and balanced with intermittent coupling phases. "Functional coupling between these two cell types is critical for the maintenance of proper bone ...

The first 'blueprint' of human skeletal development reveals how the skeleton forms, shedding light on the process of ...

A recent study identifies Neural EGFL-like 2 (NELL2), a secreted protein, as a key regulator of bone homeostasis, offering potential therapeutic applications for osteoporosis. NELL2 promotes ...

Skeletal conditions such as developmental dysplasia of the hip (DDH), osteoporosis, and osteoarthritis affect millions worldwide, often causing chronic pain and disability. These disorders stem from ...