This Journal feature begins with a case vignette highlighting a common clinical problem. Evidence supporting various strategies is then presented, followed by a review of formal guidelines, when they ...

Presence of an appendicolith is associated with a nearly twofold increased risk for undergoing appendectomy within 30 days of initiating antibiotics for appendicitis, according to a study published ...

We conducted a pragmatic, nonblinded, noninferiority, randomized trial comparing antibiotic therapy (10-day course) with appendectomy in patients with appendicitis at 25 U.S. centers. The primary ...

Acute appendicitis treated with antibiotics often ends up being treated with appendectomy, longer-term follow-up of the CODA Collaborative trial showed. In the antibiotics group, 40% had surgery to ...

The CODA investigators studied patients who had an appendicolith together and separately from other patients. The researchers randomly assigned 776 patients each to undergo appendectomy or receive a ...

Patients with an appendicolith, a calcified deposit found in about 25 per cent of cases of acute appendicitis, were associated with more complications and a higher chance of appendectomy in the first ...

Patients with an appendicolith, a calcified deposit found in about 25 per cent of cases of acute appendicitis, were associated with more complications and a higher chance of appendectomy in the first ...