The body has an intricate system to defend against infections where each type of immune cell plays a distinct role. Now, a study led by researchers from the Penn State College of Medicine has ...

Antibodies, also known as immunoglobulins, are specialized proteins that are generated by the immune system to identify and ...

A new study shows how the single-molecule organization of receptors in a cellular context determines the function of antibodies, opening up new pathways for the development of cancer immunotherapies.

Antibodies—proteins that are produced by our immune system to protect us—are crucial for recognizing and getting rid of unwanted substances, or antigens, in our body. Although their role is universal, ...

One receptor can protect antibodies from degradation, extend their half-life and become a drug target itself. Explore the ...

A new study shows how the single-molecule organization of receptors in a cellular context determines the function of antibodies, opening up new pathways for the development of cancer immunotherapies.

Stem cell transplantation (also called bone marrow transplantation) and gene therapy are among the most powerful curative ...

Deleting a single amino acid (Pro230) in the lower hinge produced half-IgG1 molecules with disrupted disulfide bonds and reoriented Fab and Fc regions, highlighting the hinge’s essential role in ...

In the aftermath of those cases, some practitioners have suggested means-plus-function claiming as one strategy to obtain antibody claims that are broader in scope than the specific antibodies ...

Researchers have analyzed the antibody Immunoglobulin M in rainbow trout to shed some light on why these proteins may have evolved over time. Antibodies -- proteins that are produced by our immune ...